Collaborative Research Centre on neurobiological mechanisms of resilience using translational approaches, including the LORA sub-study (longitudinal study on resilience with granular stress and mental health data).

The Transregional Collaborative Research Centre conducted scientific analyses of fear and anxiety by using an interdisciplinary strategy, aiming at the identification of detailed mechanisms and allowing translational approaches, thereby paving the way for novel avenues in diagnosis, therapy and identification of individual risk profiles. 

The consortium aims to unlock the neurobiological and psychological mechanisms behind placebo treatment expectation effects, understand differences between individual patients and examine how the results can be applied to everyday clinical practice.

The purpose of this CRC is to understand perception across a wide range of domains in terms of three underlying principles: Prediction, Valuation and Categorization, and their relevance for selected mental disorders.

The aims the German wide consortium integrates clinical and neurobiological associations of genetic and environmental risk factors and their interaction involved in the etiology, onset and course of affective disorders, in a large human, deeply phenotyped cohort parallelised with animal models.

This research unit will delineate the role of TSPO as a diagnostic and therapeutic target in the nervous system. It can provide animal models for anxiety and depression. Moreover, it perforrmes translational proof of concept studies with TSPO ligands and  neuroimaging.

Approach and avoidance behaviors are studied in this Research Training Group on multiple descriptive, interferential and analytical levels with emphasis on the translation of findings from basic to applied research and from animal models towards humans.

International Research Training Group “Risks and Pathomechanisms of Affective Disorders” in collaboration with King’s College London (IoPPN). The key research goals are the examination of risk factors and pathomechanisms of affective disorders following a multi-level and multi-method approach, aiming to improve the prevention, early identification as well as treatments of affective disorders in a translational setting.

Interdisciplinary graduate school aiming to reveal important mechanisms at molecular, cellular, neuroendocrine and behavioral levels, which are likely to contribute to psychopathologies with particular focus on dysfunctions in anxiety- and depression-related behavior.