National Center of Affective Disorders (NCAD)


Area of expertise

  • Clinical psychiatry and psychotherapy
  • Neuro- and cognitive psychology
  • Basic and clinical neuroscience
  • Psychopharmacology
  • Precision medicine and biomarker
  • Digital phenotyping
  • Genetics and Epigenetics
  • Early recognition/prevention
  • Animal models
  • Large, longitudinal, deeply phenotyped, transdiagnostic cohorts
  • Epidemiology

Nosology and disorders

  • Bipolar and depressive disorders (affective disorders)
  • Treatment-resistant depression
  • Prophylaxis-resistant affective disorders
  • Suicidal behavior
  • Transdiagnostic research

Etiology and mechanisms

  • Mechanisms of action of pharmacological targets (e.g. Ketamine)
  • Neurodevelopment and affective Disorders
  • Multimodal, multi-omics, cellular and digital biomarker
  • Immune system and microbiome alterations in mental disorders
  • Proof of concept paradigms

Diagnoses and Treatment

  • Early detection and prevention
  • Digital Mental Health interventions
  • Drug treatment trials (phase II to IV) and drug repurposing
  • Neurostimulation (ECT, TMS, tDCS, tACS, VNS, tVNS, DBS)
  • Psychotherapy trials